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matlab-based toolbox optpbn  (MathWorks Inc)


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    MathWorks Inc matlab-based toolbox optpbn
    Matlab Based Toolbox Optpbn, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/matlab-based toolbox optpbn/product/MathWorks Inc
    Average 90 stars, based on 1 article reviews
    matlab-based toolbox optpbn - by Bioz Stars, 2026-03
    90/100 stars

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    Steady-state distributions of output states were generated from the final PBN model using the <t>optPBN</t> <t>toolbox.</t> The mean and standard deviation (SD) of steady-state distribution from ten rounds of simulation (black stars [mean] and error bars [SD] on top) were compared against the experimental data from the training dataset (multi-coloured squares [mean] and error bars [SD] on bottom). Six experimental conditions as labelled on the x-axis are in the following order: DV-WT (WT[-]), DV-WT-Wortmannin (WT[W]), DV-WT-U0126 (WT[U]), DV-dMAPK (dM[-]), DV-dPI3K (dP[-]), and negative control (no doxycycline induction, ND).
    Optpbn Toolbox, supplied by SourceForge net, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    SourceForge net grid-based version of optpbn toolbox
    Steady-state distributions of output states were generated from the final PBN model using the <t>optPBN</t> <t>toolbox.</t> The mean and standard deviation (SD) of steady-state distribution from ten rounds of simulation (black stars [mean] and error bars [SD] on top) were compared against the experimental data from the training dataset (multi-coloured squares [mean] and error bars [SD] on bottom). Six experimental conditions as labelled on the x-axis are in the following order: DV-WT (WT[-]), DV-WT-Wortmannin (WT[W]), DV-WT-U0126 (WT[U]), DV-dMAPK (dM[-]), DV-dPI3K (dP[-]), and negative control (no doxycycline induction, ND).
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    MathWorks Inc optpbn
    A preliminary model structure is required as an input for the generation of <t>a</t> <t>PBN</t> model. The generated PBN models from different experimental conditions together with the corresponding measurement data are subsequently combined to generate an integrated optimisation problem which can be solved by various optimisation algorithms. Once the optimisation algorithm(s) generate sufficient amount of good parameter sets, a statistical analysis of the optimised parameter sets (i.e., of PBN's selection probabilities) is performed to indicate the identifiability and the sensitivity of parameters through the consideration on parameters' distribution. The <t>optPBN</t> scripts used for each task are given in parentheses.
    Optpbn, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/optpbn/product/MathWorks Inc
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    Steady-state distributions of output states were generated from the final PBN model using the optPBN toolbox. The mean and standard deviation (SD) of steady-state distribution from ten rounds of simulation (black stars [mean] and error bars [SD] on top) were compared against the experimental data from the training dataset (multi-coloured squares [mean] and error bars [SD] on bottom). Six experimental conditions as labelled on the x-axis are in the following order: DV-WT (WT[-]), DV-WT-Wortmannin (WT[W]), DV-WT-U0126 (WT[U]), DV-dMAPK (dM[-]), DV-dPI3K (dP[-]), and negative control (no doxycycline induction, ND).

    Journal: PLoS ONE

    Article Title: A Probabilistic Boolean Network Approach for the Analysis of Cancer-Specific Signalling: A Case Study of Deregulated PDGF Signalling in GIST

    doi: 10.1371/journal.pone.0156223

    Figure Lengend Snippet: Steady-state distributions of output states were generated from the final PBN model using the optPBN toolbox. The mean and standard deviation (SD) of steady-state distribution from ten rounds of simulation (black stars [mean] and error bars [SD] on top) were compared against the experimental data from the training dataset (multi-coloured squares [mean] and error bars [SD] on bottom). Six experimental conditions as labelled on the x-axis are in the following order: DV-WT (WT[-]), DV-WT-Wortmannin (WT[W]), DV-WT-U0126 (WT[U]), DV-dMAPK (dM[-]), DV-dPI3K (dP[-]), and negative control (no doxycycline induction, ND).

    Article Snippet: This implementation is integrated in the latest version of the optPBN toolbox (version 2.2.3) available on http://sourceforge.net/projects/optpbn .

    Techniques: Generated, Standard Deviation, Negative Control

    A preliminary model structure is required as an input for the generation of a PBN model. The generated PBN models from different experimental conditions together with the corresponding measurement data are subsequently combined to generate an integrated optimisation problem which can be solved by various optimisation algorithms. Once the optimisation algorithm(s) generate sufficient amount of good parameter sets, a statistical analysis of the optimised parameter sets (i.e., of PBN's selection probabilities) is performed to indicate the identifiability and the sensitivity of parameters through the consideration on parameters' distribution. The optPBN scripts used for each task are given in parentheses.

    Journal: PLoS ONE

    Article Title: optPBN: An Optimisation Toolbox for Probabilistic Boolean Networks

    doi: 10.1371/journal.pone.0098001

    Figure Lengend Snippet: A preliminary model structure is required as an input for the generation of a PBN model. The generated PBN models from different experimental conditions together with the corresponding measurement data are subsequently combined to generate an integrated optimisation problem which can be solved by various optimisation algorithms. Once the optimisation algorithm(s) generate sufficient amount of good parameter sets, a statistical analysis of the optimised parameter sets (i.e., of PBN's selection probabilities) is performed to indicate the identifiability and the sensitivity of parameters through the consideration on parameters' distribution. The optPBN scripts used for each task are given in parentheses.

    Article Snippet: Based on the existing functionalities of the BN/PBN toolbox , we introduce optPBN , a Matlab-based optimisation toolbox for probabilistic Boolean networks. optPBN allows for a simple generation of PBN models from rule-based Boolean modelling.

    Techniques: Generated, Selection